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2019;102:112742.e1123

In addition, AF triggered autophagy-dependent ferroptosis by blocking intracellular iron trafficking and storage to destroy iron homeostasis in human glioma, which was related to the activation of AMPK/mTOR/p70S6K signaling ( Gallic acid (GA), a natural polyhydroxy phenolic metabolite, is identified in various edible mushrooms, fruits, and vegetables

However, GSH depletion is a most characteristic finding when red blood cells are subjected to oxidative challenge, and in one careful study it has been demonstrated that during an attack of favism, the first measurable biochemical change is a decrease in NADPH, followed by a decrease in GSH, in keeping with stages 1 and 2 described earlier

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Dec 23 2003;100(26):15370-5